Pronucleate oocytes: Day 1 post-conventional IVF

PRANJALI MULEY; PRANITA BAWASKAR; PARIKSHIT ASHOK MULEY; GULSHAN BANDRE

doi:10.25259/NMJI_545_2023

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IMAGES IN MEDICINE

38 (

4

); 247-247

doi:

10.25259/NMJI_545_2023

Pronucleate oocytes: Day 1 post-conventional IVF

PRANJALI MULEY¹, PRANITA BAWASKAR¹, PARIKSHIT ASHOK MULEY¹, GULSHAN BANDRE²

1Department of Physiology and Clinical Embryology Datta Meghe Medical College, Wanadongri, Nagpur 440016, Maharashtra, India

2Department of Microbiology, Jawaharlal Nehru Medical College Sawangi (M), Wardha 442004, Maharashtra, India

Published: 2025-10-09

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[To cite: Muley P, Bawaskar P, Muley PA, Bandre G. Pronucleate oocytes: Day 1 post-conventional IVF. Natl Med J India 2025;38:247. DOI: 10.25259/NMJI_545_2023]

Pronucleate oocytes: Day 1 post-conventional IVF

Pronucleate oocytes are an early indicator of successful fertilization and play a vital role in the early stages of embryonic development after conventional in vitro fertilization (IVF).

Of the 10 oocytes analysed, 5 exhibited clear pronuclei, indicating successful fertilization. These fertilized pronucleate oocytes displayed characteristic features, including well-defined pronuclei, distinct nucleoli, and condensed chromatin. The 5 remaining oocytes showed evidence of failed fertilization. The unfertilized oocytes could be an indication of poor oocyte quality caused by ineffective sperm penetration. Embryo viability depends upon pronuclear morphology for better implantation and successful pregnancy rates. By evaluating pronuclear morphology, embryologists can predict embryos with higher implantation potential with better clinical outcomes,which refine selection protocols (Fig. 1).