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Year : 2019  |  Volume : 32  |  Issue : 6  |  Page : 349-351

Cogan syndrome: An autoimmune eye and ear disease with systemic manifestations

1 Department of Rheumatology, Adesh Institute of Medical Sciences and Research, Bathinda, Punjab, India
2 Department of Rheumatology and Clinical Immunology, Sir Ganga Ram Hospital, New Delhi, India

Correspondence Address:
Gurbir Singh Bhandari
Department of Rheumatology, Adesh Institute of Medical Sciences and Research, Bathinda, Punjab
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-258X.303611

Cogan syndrome (CS) is a rare vasculitis seen primarily in young adults. It predominantly affects eyes, ears and the heart with characteristic findings of interstitial keratitis, sensorineural hearing loss and vestibular dysfunction. A high index of suspicion is required to diagnose this rare disorder. It is one of the few vasculitis which can involve vessels of all sizes: small, medium and large. Coexistence of inflammatory bowel disease (IBD) in Cogan syndrome has been described in the literature. Immunosuppressive agents such as corticosteroids with or without steroid sparing agents are the standard of care. Early diagnosis and treatment are the cornerstone of treatment to prevent permanent damage to the ears and eyes. We describe a patient with Cogan syndrome with large vessel vasculitis and IBD. Our patient was treated with glucocorticoids and methotrexate.

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