Satisfaction and reasons for participation in a Covid-19 vaccine clinical trial

We would like to share ideas on the publication ‘Evaluation of satisfaction and reasons for participation in a Covid-19 vaccine clinical trial: A single-centre, observational study’.¹ After receiving informed consent, Kudyar et al. delivered a validated three-domain questionnaire to individuals who had taken both doses of COVOVAX^TM in a phase 3 trial and recorded their binary categorical responses (yes/no).¹ Participants in a Covid-19 vaccination trial in Mumbai were generally satisfied with the care they received, according to Kudyar et al.,¹ despite the fact that altruism was not their main motivation for signing up.

In general, public health organizations all around the world continue to struggle with the delivery of vaccines. A person is less likely to have confidence in their community’s healthcare system if they have a history of anti-vaccination sentiment. Numerous variables affect vaccination acceptability, and the pattern might alter over time.² The current report by Kudyar et al. may reflect the situation at an early stage of the Covid-19 outbreak, when vaccine is still in short supply. As a result, participating in a clinical trial may be the quickest way to receive vaccination. However, when the situation of vaccination availability changes, the pattern and reasons may change. The public’s trust in local public health crisis response will have a major impact on the success of Covid-19 public health activities.³