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Images in Medicine
35 (
6
); 372-373
doi:
10.25259/NMJI_35_6_372

Aortic, hepatic and renal artery aneurysms in autosomal dominant polycystic kidney disease

Department of Radiology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India
Correspondence to: 1999deepak@gmail.com
Licence
This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

[To cite: Kumar D, Mishra H, Prasad U. Aortic, hepatic and renal artery aneurysms in autosomal dominant polycystic kidney disease. Natl Med J India 2022;35:372–3.]

A 55-year-old woman, known case of autosomal dominant polycystic kidney disease (ADPKD), presented with generalized weakness, episodic haematuria and occasional dyspnoea for a few days. On echocardiography, aneurysm of the arch of aorta was suspected. She had a CT angiography of the thorax and abdomen vessels, which showed features of ADPKD with bilateral enlarged kidneys and multiple cysts in the kidney and liver parenchyma (Fig. 1). CT angiography showed aneurysm of the arch of aorta (measuring 3.3 cm) (Fig. 2) and two small aneurysms in the left hepatic artery (measuring 9×9 mm and 7×7 mm) and a small aneurysm in the intrarenal branch of the left renal artery (Figs 3 and 4). The right renal artery was seen to originate at the level of the superior mesenteric artery (Fig. 5).

FIG 1.
Axial portal phase computed tomography images showing (a) multiple variable-sized cysts in both kidneys, and (b) a few simple cysts in the liver
FIG 2.
Axial (a) and coronal (b) computed tomography images of the thorax at the level of arch of aorta showing a small aneurysm of the aortic arch
FIG 3.
Axial computed tomography images showing two small aneurysms of the branches of hepatic artery (red circles in a and b)
FIG 4.
Axial computed tomography image showing an aneurysm of the intrarenal segment of left renal artery (red circle); the left renal artery originated at its normal position
FIG 5.
Axial computed tomography image showing right renal artery (black arrow) arising at the same level as the superior mesenteric artery (yellow arrow); the right renal artery is otherwise normal

ADPKD is a major cause for end-stage renal disease and the presenting complaints are vague abdominal discomfort, haematuria, hypertension and urinary tract infection.1 Radiologically, numerous cysts are seen in the kidneys, liver, pancreas, spleen and seminal vesicle. Extra-renal manifestations of the disease include central nervous cysts, cardiac complications (mitral valve prolapse), diverticular disease, decreased fertility in men and aneurysmal malformation of the blood vessels.2,3 Intracranial aneurysms occur in about 6% to 20% of ADPKD patients and have a higher risk of subarachnoid haemorrhage. Aneurysms are also seen in the aorta, popliteal, splenic and coronary arteries.3 We have not been able to find published data regarding hepatic and renal artery aneurysms in ADPKD patients.

Conflict of interest

None declared

References

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  2. , . Extra-renal manifestations of autosomal dominant polycystic kidney disease (ADPKD): Considerations for routine screening and management. Nephrol Dial Transplant. 2014;29:247-54.
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  3. , , . Coexisting cystic lung disease as a rare extra-renal manifestation of autosomal dominant polycystic kidney disease. Radiol Case Rep. 2018;13:1048-52.
    [CrossRef] [PubMed] [Google Scholar]

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